A case of ocular toxicity to ethambutol--an idiosyncratic reaction?

Ocular toxicity of ethambutol.

OBJECTIVE To review the literature on ocular toxicity of ethambutol--its background, clinical presentation, toxicity characteristics, management, monitoring, and preventive measures. DATA SOURCES Literature search of Medline from 1962 to May 2005. STUDY SELECTION All related literature in English using the search formula: (ethambutol OR myambutol) AND (eye* OR ophthal* OR ocular) AND (adver...

Peripheral neuropathy associated with ethambutol.

A woman developed peripheral neuropathy and optic neuritis while receiving ethambutol in the retreatment of drug-resistant pulmonary tuberculosis. There was prompt improvement in peripheral neuropathy and the ocular symptoms following the withdrawal of the drug. The clinical events in this case suggest that occasionally symptoms of peripheral neuropathy may precede the development of optic neur...

Rapidly developing optic neuritis secondary to ethambutol: possible mechanism of injury.

Optic neuritis has been described among the toxic effects of Ethambutol. This side effect is dose related. The mean duration of Ethambutol induced optic neuritis (EON) is three months. We report a case of EON after few days of exposure to Ethambutol and the symptoms resolved after discontinuation of Ethambutol. This most likely represents an idiosyncratic reaction which is different as compared...

Ocular Toxicity Caused by Euphorbia Sap: A Case Report

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Ocular toxicity from ethambutol.